Saffron aka Bullistik La Mancha Saffron

Saffron is our blue mask, blue fawn, Greyce x TJ daughter.

Like all of the Bullistik kids, she is health screened using DNA genetic testing to screen for diseases that are most commonly seen in the French Bulldog breed

Saffron has been tested through PAWPRINT dna lab for the following:

Canine Multifocal Retinopathy – CLEAR
Degenerative Myelopathy – CLEAR
Hereditary Cataracts – CLEAR
Hyperuricosuria – CLEAR
Progressive Retinal Atophy – CARRIER/NOT AFFECTED

Common Symptoms

Progressive retinal Atrophy, cone-Rod dystrophy 4 (PRA-crd4) is an inherited eye disease affecting dogs. PRA-crd4 occurs as a result of degeneration of both rod and cone type Photoreceptor Cells of the Retina, which are important for vision in dim and bright light, respectively. Affected dogs can show symptoms of vision loss or have signs of retinal disease on veterinary ophthalmologic exam by 3 years of age. However, age of onset varies significantly in PRA-crd4 affected dogs, and has been reported from 1 to 15 years of age. Mutations in the RPGRIP1 gene show Incomplete Penetrance, meaning that not all dogs inheriting two copies of the Mutation develop clinical disease. This suggests that other unknown genetic or environmental factors may play a role in modifying disease development and progression. Although progression tends to be relatively slow, most affected dogs (especially those with an early age of onset) will progress to complete blindness.


Breed-Specific Information for the French Bulldog

The Mutation of the RPGRIP1 gene associated with progressive retinal Atrophy, cone-Rod dystrophy 4 has been identified in French Bulldogs, although its overall frequency in this breed is unknown. It is also unknown if French Bulldogs inheriting two copies of this mutation develop the clinical signs of progressive retinal atrophy, cone-rod dystrophy 4.


Saffron has also been certified clear through the Orthopedic Foundation For Animals for the following:  OFA Cardiac, OFA Hip, OFA Legg-Calves-Perthes, and OFA Patellar Luxation.  Her certificates from OFA are below.

OFA CARDIAC – Normal
OFA HIPS – GOOD
OFA LEGG-CALVES-PERTHES – Normal
OFA PATELLAS – Normal

Unfortunately, I have had to put the BULLISTIK® watermark on all of the health certifications for each of my Frenchies.  I was notified by PAWPRINT genetics that a man named Jason Trice, who apparently sells French Bulldogs, had stolen one of my health certifications from my website, altered it (poorly I might add) to scam his potential puppy buyer into believing the dam of his litter had been health screened.  Fortunately, the buyer thought the certificate looked fake and contacted PAWPRINT directly to verify.  PAWPRINT informed the puppy buyer that the certification results were factual but the certificate belonged to a French Bulldog owned by Bullistik French Bulldogs, not Jason Trice.  There are DISHONEST people selling French Bulldogs, so buyers beware and do your homework.

If you have any questions about Saffron’s health information, please contact me.